Isle of Palms Rentals

Compare 56 vacation rentals.
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USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway

Looking for a peaceful getaway to South Carolina’s sandy beaches? Our Isle of Palms vacation rentals offer tranquility, set apart from the hustle and bustle, but still close enough to enjoy the charm of Charleston. Whether you're looking for family fun or a romantic escape, the Isle of Palms has something for everyone.

Explore Isle of Palms house rentals, villas, condo rentals, and more

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House rentals

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Villas

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Condo rentals

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Popular amenities for Isle of Palms vacation rentals

Popular
Dog-friendly Hot tub Internet
Sea Cabin 121-B
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 121-B - Isle of Palms, SC

$196 avg / night
4.17 (18)
30 22nd Ave
3 Bedroom | 3 Bath | Sleeps 8

30 22nd Ave - Isle of Palms, SC

$308 avg / night
4.35 (26)
Sea Cabin 342-C
1 Bedroom | 1 Bath | Sleeps 3

Sea Cabin 342-C - Isle of Palms, SC

$363 avg / night
4.32 (47)
Port O' Call G-303
1 Bedroom | 1 Bath | Sleeps 4

Port O' Call G-303 - Isle of Palms, SC

$284 avg / night
4.76 (17)
Seagrove 5-A
1 Bedroom | 1 Bath | Sleeps 2

Seagrove 5-A - Isle of Palms, SC

$167 avg / night
3.77 (65)

View 51 more homes

Recent Isle of Palms guest reviews

We were able to easily walk to the beach and there are some great restaurants and a grocery store close by. The place was nice and clean. Would definitely stay here again.
Tiffany C. | Apr 2025
Clean home with great amenities. Highly recommend and would rebook in the future. Excellent location for the pool and beach.
Kelley W. | Apr 2025
4 mom's stayed in this condo. It was perfect! 3 rooms, 5 beds to choose from. Quiet, private. Had all the amenities we could need, though we decided not to cook. Toilet paper, laundry pids, dish soap, etc. were all provided and we really appreciated. A shared complex pool was steps from the elevator and was quiet and sunny. A further few steps and you were on the beach, which was flat and good for walking and shelling. We did have to drive 20+ minutes everywhere outside of the Wild Dunes complex but the restaurants and shopping were worth it! We would totally recommend this condo and Vacasa, and if we ever come back to this area we'd stay here again!!
Brooke D. | Apr 2025
Isle of Palms vacation rental FAQ

Yes, 25 of our Isle of Palms homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 104 of our Isle of Palms vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Isle of Palms vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Isle of Palms team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Isle of Palms, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning

Explore Isle of Palms, SC

Nestled on a beautiful barrier island, Isle of Palms is just 18 miles from Charleston and about 130 miles from Columbia. This idyllic location is perfect for beachgoers and nature lovers alike. The island's long stretches of beach are home to sea turtles, and if you’re lucky, you might witness local professionals helping these tiny creatures make their way to the ocean.

Things to do in Isle of Palms, SC

From beach fun to exploring nearby islands, there's no shortage of activities to enjoy during your stay.

Where is Isle of Palms, SC?

Located just off the coast of South Carolina, Isle of Palms is a barrier island near Charleston. It offers easy access to both the serene beauty of the ocean and the vibrant culture of Charleston, making it an ideal spot for vacationers looking to experience the best of both worlds.

Book an Isle of Palms vacation rental

Whether you're visiting for the beaches, the history, or just to unwind, our Isle of Palms vacation rentals provide the perfect retreat. With a range of homes featuring ocean views, spacious patios, and family-friendly amenities, you're sure to find a spot that fits your getaway vision. Browse our collection of Isle of Palms vacation homes and get ready for a relaxing escape on South Carolina’s coast.