Missouri Vacation Rentals

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Make Missouri your next getaway

Missouri is a state where rivers write the story, music fills the towns, and outdoor adventures are balanced by friendly hospitality. From the Ozark Mountains to the banks of the Mississippi River, Missouri offers a versatile mix of scenic landscapes, thriving cities, and historic small towns. Whether you’re paddling clear streams, exploring rock formations, or enjoying live music and great food, Missouri is a destination full of discovery.

Top Missouri property types

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House rentals

View 280 House rentals
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Apartments

View 162 Apartments
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Condo rentals

View 73 Condo rentals

Popular amenities for Missouri vacation rentals

Popular
Dog-friendly Hot tub Internet
 Table Rock Lakeview Lodge | Indoor Pool Sleeps 36
10 Bedroom | 10 Bath | Sleeps 36

Table Rock Lakeview Lodge | Indoor Pool Sleeps 36 - Hollister, MO

$745 avg / night
(excludes fees and taxes)
Luxury Lodge Near Lake • Hot Tub, Pools, Firepit & Games
7 Bedroom | 7 Bath | Sleeps 24

Luxury Lodge Near Lake • Hot Tub, Pools, Firepit & Games - Hollister, MO

$472 avg / night
(excludes fees and taxes)
Luxury Lakeview Retreat | Indoor Pool & Hot Tub
10 Bedroom | 9 Bath | Sleeps 26

Luxury Lakeview Retreat | Indoor Pool & Hot Tub - Branson, MO

$591 avg / night
(excludes fees and taxes)
Lakefront Luxury 9BR Retreat—Pools & Hot Tub
9 Bedroom | 9 Bath | Sleeps 24

Lakefront Luxury 9BR Retreat—Pools & Hot Tub - Hollister, MO

$571 avg / night
(excludes fees and taxes)
Sleeps 24 Lakefront - Arcades - 2Pools - Hot Tub
9 Bedroom | 9 Bath | Sleeps 24

Sleeps 24 Lakefront - Arcades - 2Pools - Hot Tub - Hollister, MO

$617 avg / night
(excludes fees and taxes)

View 545 more homes

Recent Missouri guest reviews

This was a work trip, but this place gave us a place to relax - Thank you
Jody P. | Jun 2026
It was spacious and comfortable with everything we needed for a great one week vacation.
Joel F. | Jun 2026
It was easy to get to! Great layout! Everything you needed for a couple nights stay!
Blake M. | Jun 2026
Missouri vacation rental FAQ

Yes, 146 of our Missouri homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 537 of our Missouri vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Missouri vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Missouri team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Missouri, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning

Why visit Missouri?

Missouri is where Southern warmth meets Midwestern resilience. It's great for family vacations, road trips, outdoor escapes, or quick weekends in cities like St. Louis or Kansas City. You’ll find winding rivers, state parks, lakefront towns, Civil War history, and some of the best BBQ in the country. And with four distinct seasons, Missouri's scenery shifts beautifully year-round, from dogwoods blooming in spring to golden Ozark trails in fall.

Whether you’re floating downriver, tapping your foot to blues, or touring vineyards near the Missouri wine country, it’s easy to find your pace here. 

Things to do in Missouri

Where to stay in Missouri

Vacation rentals in Missouri include everything from rustic cabins and riverfront lodges in the Ozarks to downtown lofts in Kansas City and St. Louis. Lakefront homes in places like Lake of the Ozarks are perfect for summer escapes, while cozy cottages and vineyard-adjacent properties make ideal weekend retreats. Rentals are popular for their space, comfort, and easy access to both nature and cultural attractions.

Whether you're coming for outdoor adventure or a food-filled city trip, Missouri's vacation homes are designed to fit every style and season of travel. 

A crossroads of comfort, nature, and culture

Missouri invites you to take your time, explore your interests, and feel more connected with nature, history, and the people you meet. From river towns to rugged bluffs and from jazz clubs to forest cabins, it’s a place that combines variety with heartfelt simplicity. Come for a weekend or stay longer, you’ll find the stories here are still being written.