South Carolina Vacation Rentals

Compare 2,488 vacation rentals.
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USA > South Carolina

Make South Carolina your next getaway

From the sun-kissed shores of Myrtle Beach to the historic charm of Charleston, South Carolina offers something for every kind of traveler. Whether you're teeing off on world-class golf courses, savoring Lowcountry cuisine, or exploring lush maritime forests, Vacasa has the perfect vacation rental for your stay.

Explore South Carolina condo rentals, house rentals, studios, and more

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Condo rentals

View 1,385 Condo rentals
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House rentals

View 412 House rentals
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Studios

View 400 Studios

Popular amenities for South Carolina vacation rentals

Popular
Dog-friendly Hot tub Internet
Yacht Club Villas 1-501
3 Bedroom | 3 Bath | Sleeps 8

Yacht Club Villas 1-501 - North Myrtle Beach, SC

$236 avg / night
Yacht Club Villas 2-304
4 Bedroom | 4 Bath | Sleeps 12

Yacht Club Villas 2-304 - North Myrtle Beach, SC

$408 avg / night
Lands End 39
3 Bedroom | 3 Bath | Sleeps 8

Lands End 39 - Hilton Head, SC

$491 avg / night
4.38 (58)
Wedgewood 423
2 Bedroom | 2 Bath | Sleeps 4

Wedgewood 423 - North Myrtle Beach, SC

$146 avg / night
The Patricia Grand 1534
0 Bedroom | 1 Bath | Sleeps 4

The Patricia Grand 1534 - Myrtle Beach, SC

$109 avg / night
4.07 (42)

View 2,483 more homes

Recent South Carolina guest reviews

Absolutely loved this house and location! Everything was perfect. Great location cleanliness was outstanding and communication was beyond my expectations! I will definitely book again in the near future! Thank you for making my birthday a great time!
Teri W. | Apr 2025
I love the fact that everything was exactly like the pictures. If not better this is one of our first trips where we weren’t disappointed in the lodging we were very, very pleased.
Dyana F. | Apr 2025
Gorgeous home. Great price for such a large place. Home was exceptionally clean. Feels like you're at a beach house instead.
Laryson B. | Apr 2025
South Carolina vacation rental FAQ

Yes, 580 of our South Carolina homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 2486 of our South Carolina vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our South Carolina vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local South Carolina team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for South Carolina, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
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Seamless check-in
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Professional cleaning

Stay where Southern hospitality meets coastal charm

Our South Carolina vacation rentals range from oceanfront condos with resort-style pools to secluded beach homes on Kiawah and Hilton Head Island. Enjoy amenities like private balconies, full kitchens, and direct beach access—all just minutes from the state's most beloved attractions.

Your South Carolina adventure starts now

Relax on the sandy shores of Folly Beach, take a scenic boat tour through the salt marshes, or immerse yourself in Charleston’s rich history and vibrant culinary scene. However you vacation, make it unforgettable with a Vacasa rental in South Carolina. Browse our homes and start planning your perfect getaway today.

Do you offer snowbird or long-term rentals in South Carolina? 

Yes, we have an excellent selection of snowbird rental properties available throughout South Carolina's coastal regions and inland destinations. Whether you prefer a cozy beach house on Hilton Head Island or a spacious villa in Myrtle Beach, our South Carolina snowbird rentals offer a welcoming escape from the cold.

Explore snowbird and long-term rentals in South Carolina >

South Carolina travel inspiration

Explore South Carolina snowbird rentals

Explore snowbird rentals in Myrtle Beach, SC

Explore long-term rentals in Hilton Head, SC

The ultimate guide to a dog-friendly East Coast vacation

Top Hilton Head Island oceanfront rentals with a pool

Travel Guide: Things to do in Charleston, SC

Travel Guide: Things to do in Myrtle Beach, SC

Top spots for surf vacation homes

Best spring break vacation spots for families

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