Edisto Island Vacation Rentals

Compare 116 vacation rentals.
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USA > South Carolina > Edisto Island

Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, duplexes, and more

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House rentals

View 86 House rentals
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Condo rentals

View 18 Condo rentals
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Duplexes

View 6 Duplexes

Popular amenities for Edisto Island vacation rentals

Popular
Dog-friendly Hot tub Internet
Luna Sea
4 Bedroom | 3.5 Bath | Sleeps 8

Luna Sea - Edisto Beach, SC

$474 avg / night
4.93 (27)
Driftwood Villa 269
1 Bedroom | 1 Bath | Sleeps 6

Driftwood Villa 269 - Edisto Beach, SC

$155 avg / night
4.12 (26)
Summerwind Villa - 406
3 Bedroom | 2 Bath | Sleeps 6

Summerwind Villa - 406 - Edisto Beach, SC

$227 avg / night
4.4 (73)
Driftwood Villa 240 -Turtle Watch
1 Bedroom | 1 Bath | Sleeps 4

Driftwood Villa 240 -Turtle Watch - Edisto Beach, SC

$161 avg / night
4.48 (23)
Driftwood Villa 262
1 Bedroom | 1 Bath | Sleeps 4

Driftwood Villa 262 - Edisto Beach, SC

$165 avg / night
4.04 (107)

View 111 more homes

Browse more vacation rental amenities in Edisto Island

Pool | Electric vehicle charger | Lake view | Lakefront | Ocean view | Oceanfront | Riverfront | Sound view | Soundfront | Water view

Recent Edisto Island guest reviews

This was such a great spot! Everything was perfect!
Carrie K. | Apr 2025
This place is just magical if you ask me. Love all the cool little touches and the quirkiness of the house. The view is just magical and the views of the marsh are spectacular. We fished and kayaked out to the ocean. Would definitely go back.
Carrie W. | Apr 2025
We had 4 days in this wonderful location, and brought 4 adults and 5 kids of all ages. Everyone was comfortable and we even had more room than we needed! Great location with lots of activities. Area was quiet and neighbors were friendly.
Devon S. | Apr 2025
Edisto Island vacation rental FAQ

Yes, 44 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 116 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Edisto Island, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning


Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.

Nearby destinations

Edisto Island   |   Edisto Beach   |   South Carolina
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